Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

Blog Article

Paravalvular leak (PVL) is a shortcoming that can erode the clinical benefits of transcatheter valve replacement (TAVR) and therefore a readily applicable method (aortography) to quantitate PVL objectively and accurately Beauty in the interventional suite is appealing to all operators.The ratio between the areas of the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR) defines the regurgitation fraction (RF).This technique has been validated in a mock circulation; a single injection in diastole was further tested in porcine and ovine models.

In the clinical setting, LVOT-AR was compared with trans-thoracic and trans-oesophageal echocardiography and cardiac magnetic resonance imaging.LVOT-AR > 17% discriminates mild from moderate aortic regurgitation on echocardiography and confers a poor prognosis in multiple registries, and justifies balloon post-dilatation.The LVOT-AR differentiates the individual performances of many old and novel Tracksuit devices and is being used in ongoing randomized trials and registries.